Metabolomics Scientist

Website Protheragen

Job Openings

Protheragen has been a non-traditional pharmaceutical company. Its main areas of interest are: 1) Helping its strategic partners that own proprietary technologies to find collaborators, licensing opportunities, and investors. 2) Identifying and incubating novel early-stage drug development platforms/programs using its internal funds.

Now that the construction for the new office building, equipped with brand new laboratories which are ideal for conducting independent life science research, is nearly completed, Protheragen is searching for talented and self-motivated scientists to fill the new space with innovative technologies and enthusiastic attitude.

Job Title: Metabolomics Scientist

The successful candidate will work closely and collaboratively with scientists on a range of academic and industrial projects employing targeted metabolomics, untargeted metabolomics and lipidomics, as well as introducing cutting-edge analytical and mass-spec techniques to solve customers’ problems.


  1. Perform LC-MS workflow for metabolomics/lipidomics including sample preparation, method development and execution, method validation, data acquisition and analysis, and report writing;
  2. Operate and maintain of mass spectrum system including but not limited to AB SCIEX QTRAP 6500, Thermo Q Exactive Plus, QQQ;
  3. Demonstrate competency in troubleshooting, optimization and implementation of challenging and innovative LC-MS/MS assays;
  4. Adhere to established Standard Operating Procedures and contribute to validation protocols, reports, and bioanalytical reports;
  5. Understanding of metabolomics literature and apply theoretical framework to solving problems.


  1. PhD, MSc or BSc in Biochemistry, Biology, Chemistry or similar Life Science;
  2. Significant experience in targeted metabolomics LC-MS method development, method validation and troubleshooting;
  3. Familiarity with metabolomics platforms including but not limited to AB QTRAP 6500, THERMO QE Plus and QQQ;
  4. Familiarity of LC-MS assay validation guidelines and GLP regulations;
  5. Familiarity with metabolite identification and profiling studies;
  6. Hands-on experience in LC/MS small molecule applications, including method development, quantification, characterization, and structure elucidation;
  7. Hands-on experience in various biological sample preparation techniques such as PP, LLE, and SPE;
  8. Hands-on experience and troubleshooting skills on LC separation techniques (i.e. RP, HILIC) and Mass Spec;
  9. Proficiency with mass spectrometry software as well as spreadsheet, word processing, and graphical computer programs.

Location: Holbrook, New York

Salary: Base salary + Bonus (negotiable based on background and experience)


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